Carthene R. Bazemore-Walker, Ph.D.

Director of Science Initiatives, Associate Professor of Chemistry

Carthene R. Bazemore-Walker, Ph.D.

Office of the Provost
201 Blair Hall
(336) 750-8049 (p)
(336) 750-2202 (f)

bazemorewalkercr@wssu.edu
Curriculum Vitae



Biography


Carthene R. Bazemore-Walker is Director of Science Initiatives and Associate Professor of Chemistry at Winston-Salem State University. Professor Bazemore-Walker's research utilizes proteomic technologies primarily for the characterization of membrane proteins, their post-translational modifications, and their binding partners. Prior to joining the faculty at Winston-Salem State University, she was a member of the faculty at Brown University, the University of Virginia, and Norfolk State University. 

Professor Bazemore-Walker graduated summa cum laude with her B.S. degree in Chemistry from Norfolk State University. She was a duel David and Lucile Packard Fellow and a University of Virginia Graduate Presidential Fellow while working on her Ph.D. degree in Chemistry with Professor Donald F. Hunt. Professor Bazemore-Walker completed her postdoctoral research at Massachusetts Institute of Technology with Professor Lawrence J. Stern and at Praecis Pharmaceuticals, Incorporated where she was Supervisor of the Mass Spectrometry group.

Professor Bazemore-Walker has taught courses in general chemistry for both majors and non-majors, analytical chemistry, and instrumental analysis. She has served on PhD dissertation committees and candidacy exams in the general areas of proteomics, chemical biology, and cell signaling. She is currently teaching Chemistry for Health Sciences Majors (CHE 1311 - spring semesters) here at WSSU.

Educational Background

  • Postdoctoral, Biological Chemistry, Massachusetts Institute of Technology
  • Ph.D., Analytical Chemistry, University of Virginia
  • B.S., Chemistry summa cum laude, Norfolk State University

Research and Projects Interests:

  • Bioanalytical Chemistry
  • Proteomics

Selected Publications:


Cao, Y. and Bazemore-Walker, C. R. “Proteomic Profiling of the Surface-exposed Cell Envelope Proteins of Caulobacter crescentus,” J Proteomics. 2014, 97:187-94. Epub 2013 Aug 21. PMID: 23973469

Leymarie N, Griffin PJ, Jonscher K, Kolarich D, Orlando R, McComb M, Zaia J, Aguilan J, Alley WR, Altmann F, Ball LE, Basumallick L, Bazemore-Walker CR, Behnken H, Blank MA, Brown KJ, Bunz SC, Cairo CW, Cipollo JF, Daneshfar R, Desaire H, Drake RR, Go EP, Goldman R, Gruber C, Halim A, Hathout Y, Hensbergen PJ, Horn DM, Hurum D, Jabs W, Larson G, Ly M, Mann BF, Marx K, Mechref Y, Meyer B, Möginger U, Neusüβ C, Nilsson J, Novotny MV, Nyalwidhe JO, Packer NH, Pompach P, Reiz B, Resemann A, Rohrer JS, Ruthenbeck A, Sanda M, Schulz JM, Schweiger-Hufnagel U, Sihlbom C, Song E, Staples GO, Suckau D, Tang H, Thaysen-Andersen M, Viner RI, An Y, Valmu L, Wada Y, Watson M, Windwarder M, Whittal R, Wuhrer M, Zhu Y, Zou C.. “Interlaboratory Study on Differential Analysis of Protein Glycosylation by Mass Spectrometry: the ABRF Glycoprotein Research Multi-Institutional Study 2012,” Mol Cell Proteomics. First Published on June 13, 2013, doi: 10.1074/mcp.M113.030643 mcp.M113.030643. PMID: 23764502

Poston, C. N. and Bazemore-Walker, C. R. “In-depth analysis of the mammalian mitochondria-associated membrane (MAM) proteome,” J Proteomics. 2013, 79:219-30. Epub 2013 Jan 8. PMID: 23313214

Chen, S., Lu, C., Gu, H., Mehta, A., Li, J., Romano, P., Horn, D., Hooper, D.C., Bazemore-Walker, C. R., and Block, T. “Aleuria Aurantia Lectin (AAL)-reactive immunoglobulin G rapidly appears in sera of animals following antigen exposure,” PLoS ONE 2012, 7(9): e44422. doi:10.1371/journal.pone.0044422. PMID: 23024749

Cao, Y., *Johnson, H. M. and Bazemore-Walker, C. R.  “Improved enrichment and proteomic identification of outer membrane proteins from a Gram-negative bacterium: Focus on Caulobacter crescentus,” Proteomics., 2012,12(2):251-62. Epub 2011 Dec 19. PMID: 22106052

Poston, C. N., *Duong, E., Cao, Y. and Bazemore-Walker, C. R. “Proteomic Mapping of Lipid-raft Enriched Membranes Isolated from Internal Organelles,” Biochem. Biophys. Res. Commun., 2011, 415(2):355-60. Epub 2011 Oct 20. PMID: 22037461

*indicates undergraduate author

Additional Information:

  • News
  • Honors and Awards
  • Dissertations Directed
  • Contact information

  • December 2014

    - Dr. Bazemore-Walker participates in an NSF review panel for the Directorate for Education and Human Resources (EHR).

    - Dr. Bazemore-Walker will lead WSSU’s participation in a national AAC&U student learning project. Please see university press release and Winston-Salem Journal news article.

    October 2014

    The Office of Science Initiatives begins brown bag series for STEM faculty. The theme for the 2014/15 academic year is "Applying Best Teaching Practices in the STEM Classroom."

    September 2014

    - Bazemore-Walker lab alum, Dr. Chloe Poston, begins new position as an AAAS Science & Technology Fellow for the Division of Molecular and Cellular Biosciences at NSF.

    - Dr. Bazemore-Walker becomes a mentor for the NSF-sponsored Building Connections project created and implemented by the Capstone Institute at Howard University.


    2010: Brown University Richard B. Salomon Faculty Research Award

    2009-2011: NIH NIDA Early Career Award in Chemistry of Drug Abuse and Addiction 

    2007-2009: ADVANCE at Brown University Career Development Award

    2000, 2001: American Society for Cell Biology Minority Affairs Committee Visiting Professorship Award

    1998: elected into MIT chapter of Sigma Xi Scientific Research Society

    1993-1997: David and Lucile Packard Graduate Fellowship for Chemistry, Physics, and Math

    1993-1996: University of Virginia Graduate Presidential Fellowship

    1989-1993: Norfolk State University DNIMAS "full ride" Undergraduate Science Scholarship


    PhD Dissertations Directed

    1. Zhu, Y. “Mass spectrometric analyses of protein carbonylation and glycosylation.” Brown University, PhD will be conferred May 2014.

    2. Ellisor, M. B. “Quantitative proteomic analysis of 2-methoxyestradiol induced apoptosis in MCF-7 human breast cancer cells.” Brown University, PhD conferred May 2013.

    3. Poston, C. N. “Mass spectrometry-based global proteomic analysis of endoplasmic reticulum and mitochondria contact sites.” Brown University, PhD conferred May 2013.

    4. Cao, Y. “Comprehensive studies on the outer membrane subproteome of Caulobacter crescentus using mass spectrometry based shotgun proteomics.” Brown University, PhD conferred May 2013.

    5. Gong, C. “Study of the microtubule interactome using high-performance liquid chromatography and quantitative proteomics.” Brown University, PhD conferred May 2013.

    6. Gu, H. “Mass spectrometry analysis of potential biomarker proteins.” Brown University, PhD conferred May 2012.

    Senior Honors Theses Directed

    1. Bui, A. "Statistical methods for detection of differential expression in comparative mass spectrometry-based proteomics." Senior honors thesis, Brown University, 2013.

    2. Hogan, M. J. “A proteomic approach to elucidating the mode of action of the anti-cancer agent 2-methoxyestradiol.” Senior honors thesis and departmental Clapp Prize winner for outstanding thesis in biochemistry, Brown University, 2011.

    3. Duong, E. “Exploring the relationship between the sigma-1 receptor and lipid-enriched microdomains.” Senior honors thesis and departmental Clapp Prize winner for outstanding thesis in chemistry, Brown University, 2011.

    4. Levin, S. “Toward the characterization of the Caulobacter crescentus holdfast.” Senior honors thesis, Brown University, 2010.

    Service on other dissertation/thesis committees (Brown University)

    PhD Candidacy and Dissertation Committees

    1.   Bozkurt, Ayse; Advisor: Sarah Delaney

    2.   Bruker, William J. (MPP); Advisor: Edward Hawrot

    3.   Cao, Lulu; Advisor: Arthur Salomon

    4.   Carney, Daniel; Advisor: Jason Sello

    5.   Chen, Zhuo; Advisor: Carthene Bazemore-Walker

    6.   Demirkan, Gokhan (MCB); Advisor: Philip Gruppuso

    7.   Dillion II, James T.; Advisor: Yongsong Huang

    8.   Fibiger, Dorothy; Advisor: Meredith Hastings

    9.   Guo, Xun; Advisor: David Cane

    10.  Ji, Qinqin; Advisor: Arthur Salomon

    11. Lukulay, Philip; Advisor: Amit Basu

    12. Ramirez, Teresa (MPP); Advisor: Carthene Bazemore-Walker

    13. Wang, Zhongying; Advisor: Robert Hurt

    14. Yao, Shumin; Advisor: Carthene Bazemore-Walker

    15. Yu, Kebing; Advisor: Arthur Salomon

    16. Zompa, Michael; Advisor: Christopher Seto

    Undergraduate Senior Thesis Committees (reader)

    1.   Oot (’13), Antoinette; Advisor: Wolfgang Peti

    2.   Stephenson (’12), Zoe; Advisor: Yongsong Huang


    Office and "mail to" address:
    Winston-Salem State University
    Office of the Provost, 201 Blair Hall
    601 S. Martin Luther King Jr. Drive
    Winston-Salem, NC 27110

    Lab address:
    Bowman Gray Technical Center (BGTC) Annex
    Building 630-2, Room 104
    95 W. 32nd Street
    Winston-Salem, NC 27105

Winston-Salem State University

601 S. Martin Luther King Jr. Drive

Winston-Salem, NC 27110

Phone: (336) 750-2000



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