Carthene R. Bazemore-Walker, Ph.D.

Chief Research Officer and Director of Science Initiatives

Carthene R. Bazemore-Walker, Ph.D.

Office of the Provost
205 Blair Hall
(336) 750-8049 (p)

bazemorewalkercr@wssu.edu
Curriculum Vitae



Biography


Carthene R. Bazemore-Walker serves as the Chief Research Officer and the Director of Science Initiatives for Winston-Salem State University. She has over 17 years of combined experience in the higher education, research, and biotechnology arenas. Dr. Bazemore-Walker passionately advocates for research-education synergy and works to empower faculty research endeavors in an effort to enhance student learning. Prior to joining Winston-Salem State University, she was a member of the faculty at Brown University, the University of Virginia, and Norfolk State University. 

Dr. Bazemore-Walker graduated summa cum laude with her B.S. degree in Chemistry from Norfolk State University. She was a duel David and Lucile Packard Fellow and a University of Virginia (UVa) Presidential Fellow while in graduate school, and was the first African American - man or woman - to earn a Ph.D. degree in Chemistry from UVa. Dr. Bazemore-Walker then went on to simultaneously serve as a postdoctoral fellow at MIT and as Supervisor of Mass Spectrometry at Praecis Pharmaceuticals, Inc.

Dr. Bazemore-Walker's research utilizes proteomic technologies primarily for the characterization of membrane proteins, their post-translational modifications, and their binding partners. She has served on PhD dissertation committees and candidacy exams in the general areas of proteomics, chemical biology, and cell signaling. In addition, she has taught courses in general chemistry for both majors and non-majors, analytical chemistry, and instrumental analysis. Dr. Bazemore-Walker currently teaches Chemistry for Health Sciences Majors (CHE 1311) and Research in Real Life (a new LLS 1300 course focused on hair science) here at WSSU.

Educational Background

  • Postdoctoral, Biological Chemistry, Massachusetts Institute of Technology
  • Ph.D., Analytical Chemistry, University of Virginia
  • B.S., Chemistry summa cum laude, Norfolk State University

Research and Projects Interests:

  • Bioanalytical Chemistry
  • Proteomics

Selected Publications:


Bazemore-Walker, C. R. “The (Ongoing) Plan for Student Success,” Peer Review, Winter/Spring 2016, 18 (1/2).

Cao, Y. and Bazemore-Walker, C. R. Proteomic Profiling of the Surface-exposed Cell Envelope Proteins of Caulobacter crescentus, J Proteomics. 2014, 97:187-94. Epub 2013 Aug 21. PMID: 23973469

Leymarie N, Griffin PJ, Jonscher K, Kolarich D, Orlando R, McComb M, Zaia J, Aguilan J, Alley WR, Altmann F, Ball LE, Basumallick L, Bazemore-Walker CR, Behnken H, Blank MA, Brown KJ, Bunz SC, Cairo CW, Cipollo JF, Daneshfar R, Desaire H, Drake RR, Go EP, Goldman R, Gruber C, Halim A, Hathout Y, Hensbergen PJ, Horn DM, Hurum D, Jabs W, Larson G, Ly M, Mann BF, Marx K, Mechref Y, Meyer B, M ginger U, Neus C, Nilsson J, Novotny MV, Nyalwidhe JO, Packer NH, Pompach P, Reiz B, Resemann A, Rohrer JS, Ruthenbeck A, Sanda M, Schulz JM, Schweiger-Hufnagel U, Sihlbom C, Song E, Staples GO, Suckau D, Tang H, Thaysen-Andersen M, Viner RI, An Y, Valmu L, Wada Y, Watson M, Windwarder M, Whittal R, Wuhrer M, Zhu Y, Zou C.. Interlaboratory Study on Differential Analysis of Protein Glycosylation by Mass Spectrometry: the ABRF Glycoprotein Research Multi-Institutional Study 2012, Mol Cell Proteomics. First Published on June 13, 2013, doi: 10.1074/mcp.M113.030643 mcp.M113.030643. PMID: 23764502

Poston, C. N. and Bazemore-Walker, C. R. In-depth analysis of the mammalian mitochondria-associated membrane (MAM) proteome, J Proteomics. 2013, 79:219-30. Epub 2013 Jan 8. PMID: 23313214

Chen, S., Lu, C., Gu, H., Mehta, A., Li, J., Romano, P., Horn, D., Hooper, D.C., Bazemore-Walker, C. R., and Block, T. Aleuria Aurantia Lectin (AAL)-reactive immunoglobulin G rapidly appears in sera of animals following antigen exposure, PLoS ONE 2012, 7(9): e44422. doi:10.1371/journal.pone.0044422. PMID: 23024749

Cao, Y., *Johnson, H. M. and Bazemore-Walker, C. R. Improved enrichment and proteomic identification of outer membrane proteins from a Gram-negative bacterium: Focus on Caulobacter crescentus, Proteomics., 2012,12(2):251-62. Epub 2011 Dec 19. PMID: 22106052

Poston, C. N., *Duong, E., Cao, Y. and Bazemore-Walker, C. R. Proteomic Mapping of Lipid-raft Enriched Membranes Isolated from Internal Organelles, Biochem. Biophys. Res. Commun., 2011, 415(2):355-60. Epub 2011 Oct 20. PMID: 22037461

*indicates undergraduate author

Additional Information:

  • Dissertations/Theses Directed
  • Honors and Awards
  • Contact information

  • PhD Dissertations Directed

    1. Cao, Y. “Comprehensive studies on the outer membrane subproteome of Caulobacter crescentus using mass spectrometry-based shotgun proteomics.” PhD conferred May 2013. Current position: Associate Director II at WuXi AppTec Pharmaceuticals

    2. Ellisor, M. B. “Quantitative proteomic analysis of 2-methoxyestradiol induced apoptosis in MCF-7 human breast cancer cells.” PhD conferred May 2013. Current position: Research Chemist at NIST 

    3. Gong, C. “Study of the microtubule interactome using high-performance liquid chromatography and quantitative proteomics.” PhD conferred May 2013. Current position: Scientist at NantOmics – a NantWorks company

    4. Gu, H. “Mass spectrometry analysis of potential biomarker proteins.” PhD conferred May 2012. Current position: Senior Scientist at Cell Signaling Technology

    5. Poston, C. N. “Mass spectrometry-based global proteomic analysis of endoplasmic reticulum and mitochondria contact sites.” PhD conferred May 2013. Current position: Program and Policy Task Manager at Ripple Effect Communications, Inc.

    6. Zhu, Y. “Mass spectrometric analyses of protein carbonylation and glycosylation.” PhD May 2014. Current position: Scientist at Cell Signaling Technology

    Senior Honors Theses Directed

    1. Bui, A. "Statistical methods for detection of differential expression in comparative mass spectrometry-based proteomics." Senior honors thesis, 2013. Current position: MD/MSCR candidate at the Icahn School of Medicine at Mount Sinai

    2. Duong, E. “Exploring the relationship between the sigma-1 receptor and lipid-enriched microdomains.” Senior honors thesis and departmental Clapp Prize winner for outstanding thesis in Chemistry, 2011. Current position: PhD graduate student in the Department of Biology at MIT

    3. Hogan, M. J. “A proteomic approach to elucidating the mode of action of the anti-cancer agent 2-methoxyestradiol.” Senior honors thesis and departmental Clapp Prize winner for outstanding thesis in Biochemistry, 2011. Current position: PhD candidate in Cell and Molecular Biology (in the Microbiology/Virology/Parasitology track) at the Perelman School of Medicine at the University of Pennsylvania

    4. Levin, S. “Toward the characterization of the Caulobacter crescentus holdfast.” Senior honors thesis, 2010. Current position: MD in the Harvard Neurology Residency program at Brigham and Women’s Hospital & Massachusetts General Hospital

    Service on other dissertation/thesis committees (Brown University)

    PhD Candidacy and Defense Committees (served as member, unless otherwise indicated, from 2006-13)

    1. Ayse Bozkurt, Advisor: Sarah Delaney

    2. William J. Bruker (Molecular Pharmacology and Physiology program), Advisor: Edward Hawrot

    3. Lulu Cao, Advisor: Arthur Salomon

    4. Daniel Carney, Advisor: Jason Sello

    5. Zhou Chen, Advisor: Carthene Bazemore-Walker, 2010-2013; Arthur Salomon, 2013-2016

    6. Gokhan Demirkan (Molecular Biology, Cell Biology and Biochemistry program), Advisor: Philip Gruppuso

    7. James T. Dillion II, Advisor: Yongsong Huang

    8. Dorothy Fibiger, Advisor: Meredith Hastings

    9. Xun Guo, Advisor: David Cane

    10. Qinqin Ji, Advisor: Arthur Salomon

    11. Philip Lukulay, Advisor: Amit Basu

    12. Teresa Ramirez, Advisor: Carthene Bazemore-Walker, 2008-2010; Suzanne de la Monte, 2010-2013

    13. Zhongying Wang, Advisor: Robert Hurt

    14. Shumin Yao, Advisor: Carthene Bazemore-Walker, 2010-2013

    15. Kebing Yu, Advisor: Arthur Salomon

    16. Michael Zompa, Advisor: Christopher Seto

    Undergraduate Senior Thesis Committees (served as reader from 2012-2013)

    1. Antoinette Oot; Advisor: Wolfgang Peti

    2. Zoe Stephenson; Advisor: Yongsong Huang


    2010: Richard B. Salomon Faculty Research Award

    2009-2011: NIH NIDA Early Career Award in Chemistry of Drug Abuse and Addiction

    2007-2009: ADVANCE at Brown University Career Development Award

    2000, 2001: American Society for Cell Biology Minority Affairs Committee Visiting Professorship Award

    1998: elected into Sigma Xi Scientific Research Society, MIT chapter

    1993-1997: David and Lucile Packard Graduate Fellowship for Chemistry, Physics, and Math

    1993-1996: University of Virginia Graduate Presidential Fellowship

    1992: elected into Beta Kappa Chi National Scientific Honor Society, NSU chapter

    1991: General Mills Research and Development Scholarship

    1990: elected into Alpha Kappa Mu National Honor Society, NSU chapter

    1989-1993: Norfolk State University Dozoretz National Institute for Mathematics and Applied Sciences Scholarship (full tuition, room, board, and supplies)


    Office and "mail to" address:
    Winston-Salem State University
    Office of the Provost, 205 Blair Hall
    601 S. Martin Luther King Jr. Drive
    Winston-Salem, NC 27110


Winston-Salem State University

601 S. Martin Luther King Jr. Drive

Winston-Salem, NC 27110

Phone: (336) 750-2000



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